Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Chromium Release Assay.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8979-9_12
Abstract: Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism in which immune cell activation is induced by the cross-linking of CD16 with the Fc region of antibodies that at the same time bind specifically to cell surface… read more here.
Keywords: cell mediated; antibody; dependent cell; antibody dependent ... See more keywords
Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Flow Cytometry.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8979-9_13
Abstract: Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism in which immune cell activation is induced by the cross-linking of CD16 with the Fc region of antibodies that at the same time bind specifically to cell surface… read more here.
Keywords: cell mediated; antibody; dependent cell; antibody dependent ... See more keywords
SH3 dependent cell death signaling of the avian chB6 alloantigen.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.09.009
Abstract: In chickens, B cells develop in the bursa of Fabricius, a unique organ for B cell development. Most B cells will die within the bursa, mirroring cell losses seen in mammalian bone marrow as central… read more here.
Keywords: sh3 dependent; chb6; alloantigen; dependent cell ... See more keywords
Ageing of T-dependent B cell responses.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology letters"
DOI: 10.1016/j.imlet.2021.03.012
Abstract: The human immune system is in continuous interaction with environmental factors (pathogens, exercise, stress, pollutants, diet, vaccines, and therapeutics) that condition its efficiency by promoting or moderating multiple immune mechanisms. While the deleterious impact of… read more here.
Keywords: cell responses; dependent cell; immune system; cell ... See more keywords
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09690-0
Abstract: RIPK1 regulates cell death and inflammation through kinase-dependent and -independent mechanisms. As a scaffold, RIPK1 inhibits caspase-8-dependent apoptosis and RIPK3/MLKL-dependent necroptosis. As a kinase, RIPK1 paradoxically induces these cell death modalities. The molecular switch between… read more here.
Keywords: death; dependent cell; ripk1 kinase; cell death ... See more keywords
Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response
Sign Up to like & getrecommendations! Published in 2021 at "Oncoimmunology"
DOI: 10.1080/2162402x.2021.1936392
Abstract: ABSTRACT The antibody-dependent cellular cytotoxicity (ADCC) effector function of natural killer (NK) cells is one of the known mechanisms of action for rituximab-based anti-cancer immunotherapy. Inhibition of the ADCC function of NK cells through interactions… read more here.
Keywords: rituximab dependent; kir ligands; cell; dependent cell ... See more keywords
Abstract A19: Discovery and characterization of selective and nonselective inhibitors of ErbB4 signaling: Putative targeted melanoma therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.mel2019-a19
Abstract: Introduction: Gain-of-function mutations in the gene that encodes the ErbB4 receptor tyrosine kinase have been found in a significant fraction of melanoma samples. Melanoma cell lines that harbor some of these mutations are dependent on… read more here.
Keywords: discovery; erbb4 dependent; melanoma; proliferation ... See more keywords
ISG20L1 acts as a co-activator of DAPK1 in the activation of p53 dependent cell death pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cell science"
DOI: 10.1242/jcs.260915
Abstract: Our previous studies reveal that GADD45α is a liable proapoptotic protein, which undergoes MDM2 dependent constitutive ubiquitination and degradation in resting cancer cells. Under chemotherapeutic agents (such as arsenite, 5-Fu, VP-16) exposure, DAPK1 functions as… read more here.
Keywords: cell death; cell; dependent cell; p53 dependent ... See more keywords
Tat-exported peptidoglycan amidase-dependent cell division contributes to Salmonella Typhimurium fitness in the inflamed gut
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007391
Abstract: Salmonella enterica serovar Typhimurium (S. Tm) is a cause of food poisoning accompanied with gut inflammation. Although mucosal inflammation is generally thought to be protective against bacterial infection, S. Tm exploits the inflammation to compete… read more here.
Keywords: tat exported; amia amic; cell division; dependent cell ... See more keywords
Response: Commentary: Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00466
Abstract: The commentary by Schroder et al. on our report “Belatacept Does Not Inhibit Follicular T Cell- Dependent B-Cell Differentiation in Kidney Transplantation,” challenges our findings and conclusions by questioning the methodology, definitions and interpretation of… read more here.
Keywords: follicular cell; belatacept inhibit; inhibit follicular; cell dependent ... See more keywords
From CD16a Biology to Antibody-Dependent Cell-Mediated Cytotoxicity Improvement
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.913215
Abstract: Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent cytotoxic mechanism that is mainly mediated in humans by natural killer (NK) cells. ADCC mediates the clinical benefit of several widely used cytolytic monoclonal antibodies (mAbs), and increasing… read more here.
Keywords: cell; antibody dependent; dependent cell; cell mediated ... See more keywords