CFTR‐dependent chloride efflux in cystic fibrosis mononuclear cells is increased by ivacaftor therapy
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DOI: 10.1002/ppul.23712
Abstract: The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) potentiator ivacaftor (Kalydeco®) improves clinical outcome in G551D cystic fibrosis (CF) patients. Here, we have investigated whether ivacaftor has a clinical impact on non‐G551D gating mutations and function… read more here.
Keywords: ivacaftor; cystic fibrosis; fibrosis; cftr dependent ... See more keywords