Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19700-1
Abstract: Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order organization of more than one nucleosome. We show the yeast ISW1a remodeler… read more here.
Keywords: chromatin; dinucleosome specificity; atp dependent; transcription regulation ... See more keywords
RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Nature genetics"
DOI: 10.1038/s41588-018-0060-9
Abstract: Ten-eleven translocation (TET) proteins play key roles in the regulation of DNA-methylation status by oxidizing 5-methylcytosine (5mC) to generate 5-hydroxymethylcytosine (5hmC), which can both serve as a stable epigenetic mark and participate in active demethylation.… read more here.
Keywords: gene regulation; chromatin targeting; rna dependent; chromatin ... See more keywords
The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx636
Abstract: Chd1 (Chromodomain Helicase DNA Binding Protein 1) is a conserved ATP-dependent chromatin remodeler that maintains the nucleosomal structure of chromatin, but the determinants of its specificity and its impact on gene expression are not well… read more here.
Keywords: chd1; chromatin; atp dependent; chromatin remodeler ... See more keywords
SWI/SNF-Dependent Chromatin Remodeling Protects Genome Integrity.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2021-073
Abstract: The SWI/SNF complex ATPase BRG1 prevented R-loop-associated transcription-replication conflicts. read more here.
Keywords: remodeling protects; chromatin remodeling; dependent chromatin; swi snf ... See more keywords