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Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.05.016
Abstract: We examined complement-dependent cytotoxicity (CDC) by hexamer formation-enhanced CD20 mAb Hx-7D8 of patient-derived chronic lymphocytic leukemia (CLL) cells that are relatively resistant to CDC. CDC was analyzed in normal human serum (NHS) and serum from…
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Keywords:
complement dependent;
dependent cytotoxicity;
enhanced cd20;
cdc ... See more keywords
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Published in 2020 at "Materials Chemistry and Physics"
DOI: 10.1016/j.matchemphys.2020.122946
Abstract: Abstract Engineered metal-oxide nanoparticles have greatly been used in various bio-applications, but their physicochemical properties change dramatically within a bio-system. Therefore, the development of new metal-oxide nanoparticles and proper understanding of their toxicity profile in…
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Keywords:
zinc orthostannate;
zinc;
crystalline zinc;
dependent cytotoxicity ... See more keywords
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Published in 2017 at "Transplantation"
DOI: 10.1097/01.tp.0000520368.38205.54
Abstract: Forty-two patients were evaluated for donor specific anti HLA sensi tion before they recivied ABO incompatible kidney transplantation. E recipient was evaluated by complement dependent cytotoxicity (C crossmatch, flow crossmatch, single antigen bead assay (SAB)…
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Keywords:
antibody;
dependent cytotoxicity;
abmr;
antibody mediated ... See more keywords
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Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008145
Abstract: Rationale: Human leukocyte antigen (HLA) is the major immunologic barrier in kidney transplantation (KT). Various desensitization protocols to overcome the HLA barrier have increased the opportunity for transplantation in sensitized patients. In addition, technological advances…
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Keywords:
complement dependent;
kidney transplantation;
dependent cytotoxicity;
transplantation ... See more keywords
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Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.155636
Abstract: Two HER2-specific mAbs, trastuzumab and pertuzumab (T+P), combined with chemotherapy comprise standard-of-care treatment for advanced HER2+ breast cancers (BC). While this antibody combination is highly effective, its synergistic mechanism-of-action (MOA) remains incompletely understood. Past studies…
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Keywords:
complement dependent;
her2;
combination;
therapy ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095208
Abstract: Inhibition of complement activation via the overexpression of complement-regulatory proteins (CRPs), most notably CD46, CD55 and CD59, is an efficient mechanism of disguise of cancer cells from a host immune system. This phenomenon extends to…
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Keywords:
cd20;
complement dependent;
complement;
dependent cytotoxicity ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213878
Abstract: The massive accumulation of plastics over the decades in the aquatic environment has led to the dispersion of plastic components in aquatic ecosystems, invading the food webs. Plastics fragmented into microplastics can be bioaccumulated by…
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Keywords:
microplastics mps;
dose dependent;
dependent cytotoxicity;
cytotoxicity polypropylene ... See more keywords