RNA helicases are hubs that orchestrate exosome-dependent 3'-5' decay.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2020.09.010
Abstract: The RNA exosome is a conserved complex of proteins that mediates 3'-5' RNA processing and decay. Its functions range from processing of non-coding RNAs such as ribosomal RNAs and decay of aberrant transcripts in the… read more here.
Keywords: decay; exosome; rna helicases; dependent decay ... See more keywords
Palmitate inhibits arthritis by inducing t-bet and gata-3 mRNA degradation in iNKT cells via IRE1α-dependent decay
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DOI: 10.1038/s41598-017-14780-4
Abstract: Long chain fatty acids (LCFAs) exert pro-inflammatory effects in vivo. However, little is known regarding the effect of LCFAs on invariant (i) NKT cell functions. Here, we report an inhibitory effect of saturated LCFAs on… read more here.
Keywords: gata bet; degradation; inkt; ire1 dependent ... See more keywords