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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7165-7_16
Abstract: Whole-genome bisulfite sequencing (WGBS) has become a powerful tool to dissect genome-wide methylation profiles at single-base resolution. In this chapter we describe in detail the bioinformatics pipeline used for the analysis of ARGONAUTE-dependent DNA methylation…
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Keywords:
genome wide;
methylation;
argonaute dependent;
dependent dna ... See more keywords
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Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0574-7
Abstract: It is not generally appreciated that DNA repair machinery has a critical role in the remodeling of neurons that adopt a regenerative phenotype. We identified that breast cancer 1 (BRCA1)-dependent DNA activity, previously well known…
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Keywords:
response;
dna;
brca1;
dependent dna ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98155-w
Abstract: DNA ligases, the enzymes responsible for joining breaks in the phosphodiester backbone of DNA during replication and repair, vary considerably in size and structure. The smallest members of this enzyme class carry out their functions…
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Keywords:
dna;
atp dependent;
virus;
dna ligases ... See more keywords
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Published in 2019 at "Carcinogenesis"
DOI: 10.1093/carcin/bgz101
Abstract: Insulinoma-associated protein 1 (INSM1), a zinc finger transcriptional factor, is proven to be deregulated in several types of cancers. However, comprehension of the molecular mechanism of INSM1-mediated tumor progression remains poor. Here, we show that…
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Keywords:
repair machinery;
dna repair;
cyclin dependent;
insm1 ... See more keywords