Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.035
Abstract: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhancement (ADE). A panel of… read more here.
Keywords: enhancement ebola; infection; dependent enhancement; antibody dependent ... See more keywords
Structural perspectives of antibody-dependent enhancement of infection of dengue virus.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2019.02.002
Abstract: Dengue virus (DENV) consists of four serotypes. Sequential serotype infections can cause increased disease severity, likely due to antibody-dependent enhancement (ADE) of infection. Here, we review two recent papers showing major advancements in the understanding… read more here.
Keywords: dengue virus; virus; dependent enhancement; antibody dependent ... See more keywords
Antibody-dependent enhancement of coronavirus
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2020.09.015
Abstract: Antibody-dependent enhancement (ADE) exists in several kinds of virus. It has a negative influence on antibody therapy for viral infection. This effect was first identified in dengue virus and then was also described for coronavirus.… read more here.
Keywords: enhancement coronavirus; antibody; dependent enhancement; antibody dependent ... See more keywords
Zika Virus Vaccine: The Current State of Affairs and Challenges Posed by Antibody-Dependent Enhancement Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0082
Abstract: Infection caused by the Zika virus (ZIKV) can lead to serious neurological complications such as microcephaly in neonates. At present, no approved ZIKV vaccine is available, but few vaccine candidates are undergoing clinical trial. One… read more here.
Keywords: antibody dependent; dependent enhancement; zikv; vaccine ... See more keywords
Understanding antibody-dependent enhancement in dengue: Are afucosylated IgG1s a concern?
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011223
Abstract: Dengue is a mosquito-borne infection caused by dengue virus (DENV) of the Flaviviridae family. There are four distinct serotypes, DENV-1,-2,-3,-4, which cause outbreaks globally. Infection is often self-resolving, and lifelong immunity against the infecting serotype… read more here.
Keywords: antibody dependent; dengue; infection; dependent enhancement ... See more keywords
Development of a rapid assay system for detecting antibody-dependent enhancement of dengue virus infection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of virological methods"
DOI: 10.2139/ssrn.4170692
Abstract: Antibody-dependent enhancement (ADE) is one of the pathogenic mechanisms related to disease severity in dengue virus infection. Conventional assays for detecting ADE activity usually require several days. In this study, we established a rapid assay… read more here.
Keywords: antibody dependent; virus infection; assay; rapid assay ... See more keywords
Antibody-Dependent Enhancement and Zika: Real Threat or Phantom Menace?
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2018.00044
Abstract: Mosquito-borne flaviviruses are (re-)emerging pathogens responsible for several human diseases that lately have been raising alarms both socially and in healthcare. Colonization of new geographical areas by vectors and spread of ZIKV to regions with… read more here.
Keywords: dependent enhancement; real threat; enhancement zika; zika real ... See more keywords
Plant-Produced Anti-Zika Virus Monoclonal Antibody Glycovariant Exhibits Abrogated Antibody-Dependent Enhancement of Infection
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11040755
Abstract: Monoclonal antibodies (mAb) against the envelope (E) protein of Zika virus (ZIKV) have shown great potential as therapeutics against the Zika epidemics. However, their use as a therapy may predispose treated individuals to severe infection… read more here.
Keywords: antibody dependent; infection; dependent enhancement; zika virus ... See more keywords
Prior COVID-19 Immunization Does Not Cause IgA- or IgG-Dependent Enhancement of SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11040773
Abstract: Antibody-dependent enhancement (ADE) can increase the rates and severity of infection with various viruses, including coronaviruses, such as MERS. Some in vitro studies on COVID-19 have suggested that prior immunization enhances SARS-CoV-2 infection, but preclinical… read more here.
Keywords: immunization; infection; dependent enhancement; cov infection ... See more keywords
Is antibody-dependent enhancement playing a role in COVID-19 pathogenesis?
Sign Up to like & getrecommendations! Published in 2020 at "Swiss medical weekly"
DOI: 10.4414/smw.2020.20249
Abstract: The pathogenesis of COVID-19 is currently believed to proceed via both directly cytotoxic and immune-mediated mechanisms. An additional mechanism facilitating viral cell entry and subsequent damage may involve the so-called antibody-dependent enhancement (ADE). read more here.
Keywords: dependent enhancement; pathogenesis; covid; antibody dependent ... See more keywords
miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.62621
Abstract: Dietary restriction (DR) extends healthy lifespan in diverse species. Age and nutrient-related changes in the abundance of microRNAs (miRNAs) and their processing factors have been linked to organismal longevity. However, the mechanisms by which they… read more here.
Keywords: enhancement lifespan; dietary restriction; lifespan; mir 125 ... See more keywords