The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Leukocyte Biology"
DOI: 10.1093/jleuko/qiae105
Abstract: Abstract Intestinal eosinophils express the aryl hydrocarbon receptor (AHR), an environmental sensor and ligand-activated transcription factor that responds to dietary or environmental ligands. AHR regulates tissue adaptation, survival, adhesion, and immune functions in intestinal eosinophils.… read more here.
Keywords: limits expression; dependent genes; intestinal eosinophils; ahr dependent ... See more keywords
Promoters of ASCL1‐ and NEUROD1‐dependent genes are specific targets of lurbinectedin in SCLC cells
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202114841
Abstract: Small‐Cell Lung Cancer (SCLC) is an aggressive neuroendocrine malignancy with a poor prognosis. Here, we focus on the neuroendocrine SCLC subtypes, SCLC‐A and SCLC‐N, whose transcription addiction was driven by ASCL1 and NEUROD1 transcription factors… read more here.
Keywords: promoters ascl1; transcription; ascl1 neurod1; dependent genes ... See more keywords