The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
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DOI: 10.7150/thno.51631
Abstract: Objectives: Mesenchymal Stem/Stromal Cells (MSC) are promising therapeutic tools for inflammatory diseases due to their potent immunoregulatory capacities. Their suppressive activity mainly depends on inflammatory cues that have been recently associated with changes in MSC… read more here.
Keywords: atp synthase; glycolytic switch; dependent glycolytic; ampk dependent ... See more keywords