Integration of purinergic and angiotensin II receptor function in renal vascular responses and renal injury in angiotensin II-dependent hypertension
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DOI: 10.1007/s11302-019-09662-5
Abstract: Glomerular arteriolar vasoconstriction and tubulointerstitial injury are observed before glomerular damage occurs in models of hypertension. High interstitial ATP concentrations, caused by the increase in arterial pressure, alter renal mechanisms involved in the long-term control… read more here.
Keywords: angiotensin dependent; dependent hypertension; hypertension; angiotensin ... See more keywords
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension
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DOI: 10.1038/s41467-020-18538-x
Abstract: Myeloid cells are known mediators of hypertension, but their role in initiating renin-induced hypertension has not been studied. Vitamin D deficiency causes pro-inflammatory macrophage infiltration in metabolic tissues and is linked to renin-mediated hypertension. We… read more here.
Keywords: secretion; dependent hypertension; macrophage; hypertension ... See more keywords
Abstract 142: Purinergic P2 X Receptors and a T 1 Receptors Share Post - Receptor Signaling Pathways Regulating Renal Afferent Arterioles in Angiotensin I I ( Ang I I) Dependent Hypertension
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DOI: 10.1161/hyp.74.suppl_1.142
Abstract: In Ang II dependent hypertension, the increased afferent arteriolar resistance (AAR) is assumed to be primarily due to the increased intrarenal levels of Ang II activating AT1 receptors. Because the renal interstitial ATP levels increase… read more here.
Keywords: signaling pathways; post receptor; dependent hypertension; ang dependent ... See more keywords