Electrical pulse stimulation induces GLUT4 translocation in a Rac‐Akt‐dependent manner in C2C12 myotubes
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.12982
Abstract: Muscle contraction increases skeletal muscle glucose uptake, but the underlying mechanisms are not fully elucidated. While important for insulin‐stimulated glucose uptake, the role of Akt in contraction‐stimulated muscle glucose uptake is controversial. In our study,… read more here.
Keywords: electrical pulse; pulse stimulation; glut4 translocation; translocation ... See more keywords
Reductants fuel lytic polysaccharide monooxygenase activity in a pH‐dependent manner
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14629
Abstract: Polysaccharide‐degrading mono‐copper lytic polysaccharide monooxygenases (LPMOs) are efficient peroxygenases that require electron donors (reductants) to remain in the active Cu(I) form and to generate the H2O2 co‐substrate from molecular oxygen. Here, we show how commonly… read more here.
Keywords: lytic polysaccharide; dependent manner; fuel lytic; reductants fuel ... See more keywords
Human MAIT cells are rapidly activated by Aspergillus spp. in an APC‐dependent manner
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747312
Abstract: Mucosal associated invariant T cells (MAIT cells) are innate‐like T cells (TC) which are known to be activated by several bacteria and viruses. However, activation of MAIT cells by moulds, such as the opportunistic human… read more here.
Keywords: mait cells; dependent manner; mait; apc dependent ... See more keywords
M2e‐specific antibodies protect against influenza PR8 virus in an isotype and route dependent manner
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28721
Abstract: The ectodomain of influenza matrix protein 2 (M2e) is a promising target for the development of universal prophylactic and therapeutic agents against influenza viruses of different subtypes. We constructed three M2e‐specific monoclonal antibody variants, M2A1‐1… read more here.
Keywords: protection; influenza pr8; m2e specific; m2e ... See more keywords
Vitamin D protects against particles‐caused lung injury through induction of autophagy in an Nrf2‐dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22726
Abstract: Fine particulate matter is a well‐known air pollutant threatening public health. Studies have confirmed long‐term exposure to the particles could decrease the pulmonary function, induce asthma exacerbation, and chronic obstructive pulmonary disease, as well as… read more here.
Keywords: nrf2 dependent; autophagy nrf2; induced pulmonary; induction autophagy ... See more keywords
Assessment of Waterborne Amine-Coated Silver Nanoparticle (Ag-NP)-Induced Toxicity in Labeo rohita by Histological and Hematological Profiles
Sign Up to like & getrecommendations! Published in 2017 at "Biological Trace Element Research"
DOI: 10.1007/s12011-017-1080-5
Abstract: Silver nanoparticles (Ag-NPs) have wide applications in the medical field; however, the toxicological effects are still poorly studied. The study was aimed to determine the effects of 15.78 nm spherical and amine-coated Ag-NPs on hematology and… read more here.
Keywords: dose dependent; assessment waterborne; amine coated; labeo rohita ... See more keywords
Evaluation of Lead Chloride Toxicity on Lipid Profile in Venus verrucosa Gills
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Environmental Research"
DOI: 10.1007/s41742-019-00218-4
Abstract: The present study aimed to investigate the effects of lead chloride (PbCl2) exposure at graded concentrations on the gills of Venus verrucosa. Clams were randomly divided into four groups: group 1 severed as control and… read more here.
Keywords: venus verrucosa; dependent manner; toxicity; chloride ... See more keywords
YAF2 exerts anti-apoptotic effect in human tumor cells in a FANK1- and phosphorylation-dependent manner.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.105
Abstract: YY1-associated factor 2 (YAF2) was frequently reported to modulate target gene transcription through both epigenetic and non-epigenetic means. However, other mechanisms were also utilized by YAF2 to carry out its biological functions. Here, we demonstrated… read more here.
Keywords: phosphorylated yaf2; dependent manner; tumor cells; human tumor ... See more keywords
Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119833
Abstract: Engineering a pro-regenerative immune response following scaffold implantation is integral to functional tissue regeneration. The immune response to implanted biomaterials is determined by multiple factors, including biophysical cues such as material stiffness, topography and particle… read more here.
Keywords: immune; macrophage polarization; particle; msc osteogenesis ... See more keywords
Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.020
Abstract: Telomerase, the end-replication enzyme, is reactivated in malignant cancers to drive cellular immortality. While this distinction makes telomerase an attractive target for anti-cancer therapies, most approaches for inhibiting its activity have been clinically ineffective. As… read more here.
Keywords: telomerase; telomerase dependent; dependent manner; cell death ... See more keywords
Persimmon tannin changes the properties and the morphology of wheat gluten by altering the cross-linking, and the secondary structure in a dose-dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Food research international"
DOI: 10.1016/j.foodres.2020.109536
Abstract: The effects of persimmon tannin (PT) on the texture, viscoelasticity, thermal stability, and morphology of gluten were studied and the underlying mechanisms were also explored. The results showed that PT increased the hardness and viscoelasticity… read more here.
Keywords: properties morphology; persimmon tannin; dose dependent; cross linking ... See more keywords