Visualizing tRNA-dependent mistranslation in human cells
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DOI: 10.1080/15476286.2017.1379645
Abstract: ABSTRACT High-fidelity translation and a strictly accurate proteome were originally assumed as essential to life and cellular viability. Yet recent studies in bacteria and eukaryotic model organisms suggest that proteome-wide mistranslation can provide selective advantages… read more here.
Keywords: dependent mistranslation; trna dependent; mistranslation; visualizing trna ... See more keywords
Genetic Interaction of tRNA-Dependent Mistranslation with Fused in Sarcoma Protein Aggregates
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DOI: 10.3390/genes14020518
Abstract: High-fidelity protein synthesis requires properly aminoacylated transfer RNAs (tRNAs), yet diverse cell types, from bacteria to humans, show a surprising ability to tolerate errors in translation resulting from mutations in tRNAs, aminoacyl-tRNA synthetases, and other… read more here.
Keywords: fused sarcoma; trna dependent; dependent mistranslation; trna ... See more keywords