Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2017.02.019
Abstract: Oleuropein is a primary phenolic compound found in olive leaf and Fraxinus rhynchophylla. Here, we investigated the impact of oleuropein on LPS-induced BV-2 microglial cells. Oleuropein suppressed the LPS-induced increase in pro-inflammatory mediators, such as… read more here.
Keywords: dependent mitochondrial; drp1 dependent; oleuropein; fission ... See more keywords
Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways
Sign Up to like & getrecommendations! Published in 2018 at "Food and Agricultural Immunology"
DOI: 10.1080/09540105.2017.1373271
Abstract: ABSTRACT Chlorpyrifos (CPF) has been widely used around the world as a pesticide for both agricultural and residential application. Although various studies have reported toxicity and health-related effects from CPF exposure, the potential threat and… read more here.
Keywords: dependent mitochondrial; caspase dependent; liver; potential threat ... See more keywords
Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in mice
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008050
Abstract: CENP-F is a large, microtubule-binding protein that regulates multiple cellular processes including chromosome segregation and mitochondrial trafficking at cytokinesis. This multiplicity of functions is mediated through the binding of various partners, like Bub1 at the… read more here.
Keywords: dependent mitochondrial; mitochondrial pool; cenp; miro ... See more keywords
Differential vulnerability of locus coeruleus and dorsal raphe neurons to chronic methamphetamine-induced degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.949923
Abstract: Methamphetamine (meth) increases monoamine oxidase (MAO)-dependent mitochondrial stress in axons of substantia nigra pars compacta (SNc), and ventral tegmental area (VTA) dopamine neurons. Chronic administration of meth results in SNc degeneration and MAO inhibition is… read more here.
Keywords: stress; degeneration; dependent mitochondrial; neurons chronic ... See more keywords
Nutrient-Dependent Mitochondrial Fission Enhances Osteoblast Function
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15092222
Abstract: Background: The bone synthesizing function of osteoblasts (OBs) is a highly demanding energy process that requires nutrients. However, how nutrient availability affects OBs behavior and bone mineralization remain to be fully understood. Methods: MC3T3-E1 cell… read more here.
Keywords: function; mitochondrial fission; obs; dependent mitochondrial ... See more keywords
Miro1-dependent mitochondrial dynamics in parvalbumin interneurons
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65215
Abstract: The spatiotemporal distribution of mitochondria is crucial for precise ATP provision and calcium buffering required to support neuronal signaling. Fast-spiking GABAergic interneurons expressing parvalbumin (PV+) have a high mitochondrial content reflecting their large energy utilization.… read more here.
Keywords: dynamics parvalbumin; dependent mitochondrial; parvalbumin interneurons; miro1 dependent ... See more keywords