Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa
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DOI: 10.1371/journal.ppat.1010305
Abstract: Multiple regulated neutrophil cell death programs contribute to host defense against infections. However, despite expressing all necessary inflammasome components, neutrophils are thought to be generally defective in Caspase-1-dependent pyroptosis. By screening different bacterial species, we… read more here.
Keywords: dependent pyroptosis; caspase dependent; pseudomonas aeruginosa; caspase driven ... See more keywords
Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages
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DOI: 10.3390/vaccines11010164
Abstract: Human norovirus (HNV) is one of the emerging and rapidly spreading groups of pathogens and the main cause of epidemic viral gastroenteritis globally. Due to a lack of in vitro culture systems and suitable animal… read more here.
Keywords: dependent pyroptosis; murine norovirus; pyroptosis; raw264 macrophages ... See more keywords