EGFR-Dependent Regulated Intramembrane Proteolysis of EpCAM-Letter.
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DOI: 10.1158/0008-5472.can-16-2456
Abstract: Hsu and colleagues reported on EGF/EGFR–triggered activation of regulated intramembrane proteolysis (RIP) of EpCAM that induces an EMT phenotype ([1][1]). This finding is of utmost interest, as it might explain contradicting effects of EpCAM on… read more here.
Keywords: egfr dependent; dependent regulated; intramembrane proteolysis; epcam ... See more keywords