Actin-Dependent Regulation of Borrelia burgdorferi Phagocytosis by Macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2016_26
Abstract: The spirochete Borrelia burgdorferi is the causative agent of Lyme disease, a multisystemic disorder affecting primarily skin, nervous system, and joints. If an infection with Borrelia proceeds unchecked, the disease can also enter a chronic… read more here.
Keywords: phagocytosis; dependent regulation; actin dependent; burgdorferi ... See more keywords
Activity- and sleep-dependent regulation of tonic inhibition by Shisa7
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108899
Abstract: SUMMARY Tonic inhibition mediated by extrasynaptic γ-aminobutyric acid type A receptors (GABAARs) critically regulates neuronal excitability and brain function. However, the mechanisms regulating tonic inhibition remain poorly understood. Here, we report that Shisa7 is critical… read more here.
Keywords: tonic inhibition; regulation tonic; inhibition; dependent regulation ... See more keywords
CB1R-dependent regulation of astrocyte physiology and astrocyte-neuron interactions
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108678
Abstract: The endocannabinoid system (ECS) is involved in a variety of brain functions, mainly through the activation of the type-1 cannabinoid receptors (CB1R). CB1R are highly expressed throughout the brain at different structural, cellular and subcellular… read more here.
Keywords: cb1r dependent; astrocyte; dependent regulation; physiology ... See more keywords
Photoreceptor-dependent regulation of photoprotection.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2017.03.016
Abstract: In photosynthetic organisms, proteins in the light-harvesting complex (LHC) harvest light energy to fuel photosynthesis, whereas photoreceptor proteins are activated by the different wavelengths of the light spectrum to regulate cellular functions. Under conditions of… read more here.
Keywords: regulation photoprotection; photoreceptor dependent; photoreceptor; light ... See more keywords
PKB/Akt-dependent regulation of inflammation in cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.04.018
Abstract: Chronic inflammation is a major cause of human cancer. Clinical cancer therapies against inflammatory risk factors are strategically determined. To rationally guide a novel drug development, an improved mechanistic understanding on the pathological connection between… read more here.
Keywords: akt dependent; inflammation; dependent regulation; pkb akt ... See more keywords
Dual and plasticity-dependent regulation of cerebello-zona incerta circuits on anxiety-like behaviors
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58727-0
Abstract: Clinical observation has identified cerebellar cognitive affective syndrome, which is characterized by various non-motor dysfunctions such as social disorders and anxiety. Increasing evidence has revealed reciprocal mono-/poly-synaptic connections of cerebello-cerebral circuits, forming the concept of… read more here.
Keywords: dual plasticity; plasticity dependent; zona incerta; dependent regulation ... See more keywords
micro-RNAs dependent regulation of DNMT and HIF1α gene expression in thrombotic disorders
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-38057-6
Abstract: MicroRNAs (miRNAs) are involved in a wide variety of cellular processes and post-transcriptionally regulate several mechanism and diseases. However, contribution of miRNAs functioning during hypoxia and DNA methylation together is less understood. The current study… read more here.
Keywords: gene family; micro rnas; dependent regulation; hypoxia ... See more keywords
Small GTPase-dependent regulation of leukocyte-endothelial interactions in inflammation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Society transactions"
DOI: 10.1042/bst20170530
Abstract: Inflammation is a complex biological response that serves to protect the body's tissues following harmful stimuli such as infection, irritation or injury and initiates tissue repair. At the start of an inflammatory response, pro-inflammatory mediators… read more here.
Keywords: response; adhesion; gtpase dependent; dependent regulation ... See more keywords
Matrix stiffness-dependent regulation of immunomodulatory genes in human MSCs is associated with the lncRNA CYTOR
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2404146121
Abstract: Significance Mechanotransduction, the translation of external physical cues to internal biochemical signals, influences cellular processes and behaviors. Here, we explore such mechanisms that underlie cellular responses to environmental stiffness using a 3D, tissue-mimetic culturing platform.… read more here.
Keywords: regulation immunomodulatory; cytor; dependent regulation; stiffness dependent ... See more keywords
Sorting Nexin 27-dependent regulation of Lck and CD4 tunes the initial stages of T-cell activation.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiae086
Abstract: Sorting nexin (SNX) 27 is a unique member of the SNX family of proteins that mediates the endosome-to-plasma membrane trafficking of cargos bearing a PSD95/Dlg1/ZO-1 (PDZ)-binding motif. In brain, SNX27 regulates synaptic plasticity, and its… read more here.
Keywords: snx27 expression; lck; sorting nexin; activation ... See more keywords
Abstract 1599: CD40L-dependent regulation of BIM leads to lymphoma survival and therapy resistance in protective niches
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-1599
Abstract: Mantle Cell Lymphoma (MCL), an aggressive B-cell lymphoma, is tightly dependent on the microenvironment (TME) for expansion and a dynamic cellular dialogue within lymph node (LN) niches results in ecosystem corruption and tumoral resistance. Within… read more here.
Keywords: regulation bim; resistance; bim; cell ... See more keywords