A Unique m6A-Dependent Restriction Endonuclease from an Archaeal Virus
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DOI: 10.1128/spectrum.04262-22
Abstract: Many modification-dependent restriction endonucleases (MDREs) were identified in prokaryotes and recognized modified cytosine bases, such as 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), and glucosyl-5-hydroxymethylcytosine (g5hmC). The first virus-derived MDRE (HHPV4I) from the archaeal virus HHPV4 was identified… read more here.
Keywords: hhpv4i; restriction; m6a dependent; dependent restriction ... See more keywords