Abstract 2628: Synthetic lethal targeting of ATR in alternative lengthening of telomeres-dependent rhabdomyosarcoma
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DOI: 10.1158/1538-7445.am2018-2628
Abstract: Synthetic lethal dependencies have recently emerged as tumor-specific vulnerabilities which provide broad therapeutic windows and have successfully been used for rational therapeutic target discovery. Despite intense international efforts over many decades, cure rates for patients… read more here.
Keywords: dependent rhabdomyosarcoma; alternative lengthening; rhabdomyosarcoma; lengthening telomeres ... See more keywords