Hydrogen sulfide exposure induces NLRP3 inflammasome‐dependent IL‐1β and IL‐18 secretion in human mononuclear leukocytes in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.69
Abstract: The aim was to investigate if hydrogen sulfide (H2S) induces the formation of the NLRP3 inflammasome and subsequent IL‐1β and IL‐18 secretion in human peripheral blood mononuclear cells (PBMCs) and in the human monocyte cell… read more here.
Keywords: secretion; dependent secretion; secretion human; nlrp3 inflammasome ... See more keywords
The P2X7 receptor mediates NLRP3-dependent IL-1β secretion and promotes phagocytosis in the macrophage response to Treponema pallidum.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106344
Abstract: It is unclear whether P2X7 receptor (P2X7R) mediates NOD-like receptor family protein 3 (NLRP3)-dependent IL-1β secretion and spirochete phagocytosis in syphilis. This study was conducted to investigate the role of P2X7R in modifying NLRP3-dependent IL-1β… read more here.
Keywords: secretion; dependent secretion; nlrp3 dependent; p2x7 receptor ... See more keywords