Vibrio cholerae YaeO is a structural homologue of RNA chaperone Hfq that inhibits Rho-dependent transcription termination by dissociating its hexameric state.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.09.019
Abstract: Rho-dependent transcription termination is a well conserved process in bacteria. The Psu and YaeO proteins are the two established inhibitors of the ATP-dependent RNA helicase Rho protein of E. coli. Here we show a detailed… read more here.
Keywords: transcription termination; rna; cholerae yaeo; dependent transcription ... See more keywords
E2F-dependent transcription determines replication capacity and S phase length
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DOI: 10.1038/s41467-020-17146-z
Abstract: DNA replication timing is tightly regulated during S-phase. S-phase length is determined by DNA synthesis rate, which depends on the number of active replication forks and their velocity. Here, we show that E2F-dependent transcription, through… read more here.
Keywords: phase; replication capacity; e2f dependent; dependent transcription ... See more keywords
Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
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DOI: 10.1038/s41467-021-20898-x
Abstract: Consolidated memory can be preserved or updated depending on the environmental change. Although such conflicting regulation may happen during memory updating, the flexibility of memory updating may have already been determined in the initial memory… read more here.
Keywords: rpd3 corest; dependent transcription; memory updating; memory ... See more keywords
An ENU-induced mutation in Twist1 transactivation domain causes hindlimb polydactyly with complete penetrance and dominant-negatively impairs E2A-dependent transcription
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59455-9
Abstract: Twist1 encodes a basic helix-loop-helix transcription factor (TF), which forms homodimer or heterodimer with other TFs, like E2A, to regulate target genes’ expression. Mutations in TWIST1 are associated with Saethre-Chotzen syndrome (SCS), a rare congenital… read more here.
Keywords: transcription; penetrance; twist1; dependent transcription ... See more keywords
CSB-independent, XPC-dependent transcription-coupled repair in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123163119
Abstract: Significance We have discovered that Drosophila, which does not have the canonical TCR homologs, does nevertheless carry out TCR as efficiently as organisms that do. Furthermore, using the XR-seq and in vivo excision assay we… read more here.
Keywords: xpc dependent; independent xpc; dependent transcription; xpc ... See more keywords
Decoding YAP dependent transcription in the liver
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DOI: 10.1093/nar/gkac624
Abstract: Abstract The transcriptional coactivator YAP is emerging as a master regulator of cell growth. In the liver, YAP activity is linked to hepatomegaly, regeneration, dedifferentiation, and aggressive tumor growth. Here we present genomic studies to… read more here.
Keywords: decoding yap; transcription; yap dependent; transcription liver ... See more keywords
RNA Polymerase II-Dependent Transcription Initiated by Selectivity Factor 1: A Central Mechanism Used by MLL Fusion Proteins in Leukemic Transformation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00722
Abstract: Cancer cells transcribe RNAs in a characteristic manner in order to maintain their oncogenic potentials. In eukaryotes, RNA is polymerized by three distinct RNA polymerases, RNA polymerase I, II, and III (RNAP1, RNAP2, and RNAP3,… read more here.
Keywords: fusion proteins; mll fusion; dependent transcription; fusion ... See more keywords
Sesamin Activates Nrf2/Cnc-Dependent Transcription in the Absence of Oxidative Stress in Drosophila Adult Brains
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DOI: 10.3390/antiox10060924
Abstract: Sesamin, a major lignin in sesame seeds, possesses health-promoting properties. Sesamin feeding suppresses several aging-related phenotypes such as age-dependent accumulation of damaged proteins in the muscles and neuronal loss in the brains of Drosophila adults… read more here.
Keywords: oxidative stress; cnc dependent; dependent transcription; nrf2 cnc ... See more keywords