Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy
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DOI: 10.1002/cam4.5775
Abstract: Proteasome inhibitors are in use in treating certain types of cancers. These drugs inhibit the catalytic activity of the 20S proteasome, shared by all the different proteasome complexes. Inhibitors of the 26S‐associated deubiquitinating activity explicitly… read more here.
Keywords: proteasome regulatory; depleting 19s; 19s proteasome; strategy ... See more keywords