Could α-Klotho Unlock the Key Between Depression and Dementia in the Elderly: from Animal to Human Studies.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02313-0
Abstract: α-Klotho is known for its aging-related functions and is associated with neurodegenerative diseases, accelerated aging, premature morbidity, and mortality. Recent literature suggests that α-Klotho is also involved in the regulation of mental functions, such as… read more here.
Keywords: depression; dementia; could klotho; klotho unlock ... See more keywords
Antidepressant medications in dementia: evidence and potential mechanisms of treatment-resistance
Sign Up to like & getrecommendations! Published in 2023 at "Psychological Medicine"
DOI: 10.1017/s003329172200397x
Abstract: Abstract Depression in dementia is common, disabling and causes significant distress to patients and carers. Despite widespread use of antidepressants for depression in dementia, there is no evidence of therapeutic efficacy, and their use is… read more here.
Keywords: antidepressant medications; depression dementia; dementia evidence; dementia ... See more keywords
Evidence of altered depression and dementia‐related proteins in the brains of young rats after ovariectomy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14537
Abstract: Menopause, a risk factor for brain dysfunction in women, is characterized by neuropsychological symptoms including depression and dementia, which are closely related to alterations in different brain regions after menopause. However, little is known about… read more here.
Keywords: proteins brains; dementia; dementia related; brain ... See more keywords
Effects of depression, dementia and delirium on activities of daily living in elderly patients after discharge
Sign Up to like & getrecommendations! Published in 2019 at "BMC Geriatrics"
DOI: 10.1186/s12877-019-1294-9
Abstract: BackgroundThe three geriatric conditions, depression, dementia and delirium (3D’s), are common among hospitalized older patients and often lead to impairments of activities of daily living. The aim of this study is to explore the impact… read more here.
Keywords: dementia delirium; delirium; activities daily; depression dementia ... See more keywords
Depression and Dementia in Older Adults: A Neuropsychological Review
Sign Up to like & getrecommendations! Published in 2021 at "Aging and Disease"
DOI: 10.14336/ad.2021.0526
Abstract: Depression and dementia are the most common neuropsychiatric disorders in the older adult population. There are a certain number of depressed patients who visit outpatient clinics because they suspect dementia due to similarities in the… read more here.
Keywords: review; treatment; depression dementia; dementia ... See more keywords
Discrepancies Between Community-Dwelling Individuals with Dementia and Their Proxies in Completing the Cornell Scale for Depression in Dementia: A Secondary Data Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s289595
Abstract: Background Depressive symptoms are common in people with dementia. Purpose This study examined the discrepancies in the ratings of depressive symptoms between people with dementia and their family caregivers, and the extent to which these… read more here.
Keywords: scale depression; people dementia; depression dementia; dementia ... See more keywords
Depression in Dementia or Dementia in Depression? Systematic Review of Studies and Hypotheses.
Sign Up to like & getrecommendations! Published in 2020 at "Current Alzheimer research"
DOI: 10.2174/1567205017666200217104114
Abstract: The majority of research works to date suggest that major depressive disorder (MDD) is a risk factor for dementia and may predispose to cognitive decline in both early and late onset variants. The presence of… read more here.
Keywords: depression; dementia; dementia dementia; review ... See more keywords
Perspectives on the complex links between depression and dementia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.821866
Abstract: This review highlights that depression is a growing health problem for the individual, and because of its high frequency in most societies, a growing burden on health care budgets. The focus of the review is… read more here.
Keywords: depression; depression dementia; links depression; dementia ... See more keywords