Long non‐coding RNA uc.80‐ overexpression promotes M2 polarization of microglias to ameliorate depression in rats
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DOI: 10.1002/iub.2353
Abstract: Microglia polarization is associated with the pathogenesis of depression. A previous study shows that long non‐coding RNA uc.80‐ is down‐regulated in the hippocampus of depressed rats. Thus, this article aims to investigate the role of… read more here.
Keywords: depression; overexpression; polarization microglias; polarization ... See more keywords
Effects of miR-124-3p Silencing on Neuronal Damage in the Hippocampus of Depression Rats by Regulating STAT3 Gene
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DOI: 10.1155/2022/3733656
Abstract: Objective A large amount of evidence shows that the abnormal expression of miRNA plays an important role in the development of depression. Therefore, we investigated the effect of miR-124-3p on neuronal damage in the hippocampus… read more here.
Keywords: mir 124; depression rats; silencing mir; expression ... See more keywords
Rutin Improves Anxiety and Reserpine-Induced Depression in Rats
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DOI: 10.3390/molecules27217313
Abstract: Mental disorders have a poor clinical prognosis and account for approximately 8% of the global burden of disease. Some examples of mental disorders are anxiety and depression. Conventional antidepressants have limited efficacy in patients because… read more here.
Keywords: rutin improves; effect; depression rats; depression ... See more keywords