Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-018-0269-4
Abstract: Chronic constipation is often accompanied by emotional disorders such as depression and anxiety. The aim of this study was to determine whether administration of a multispecies probiotic can decrease depressive behaviors through the gut-brain axis… read more here.
Keywords: induced constipation; akt signaling; depressive behaviors; decrease depressive ... See more keywords
Stress-Induced Epigenetic Changes in Hippocampal Mkp-1 Promote Persistent Depressive Behaviors
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-01689-4
Abstract: Chronic stress induces persistent depressive behaviors. Stress-induced transcriptional alteration over the homeostatic range in stress hormone–sensitive brain regions is believed to underlie long-lasting depressive behaviors. However, the detailed mechanisms by which chronic stress causes those… read more here.
Keywords: hdac2 suv39h1; chronic stress; mkp; depressive behaviors ... See more keywords
Swimming exercise reverses chronic unpredictable mild stress–induced depression-like behaviors and alleviates neuroinflammation and collapsing response mediator protein-2–mediated neuroplasticity injury in adult male mice
Sign Up to like & getrecommendations! Published in 2022 at "Neuroreport"
DOI: 10.1097/wnr.0000000000001779
Abstract: Objective Impaired neuroplasticity and neuroinflammation are vital in the mechanisms of depression. Exercise alleviates depressive symptoms and ameliorates body functions. Swimming is one of the most common exercises; however, whether swimming alters depressive behaviors and… read more here.
Keywords: depressive behaviors; swimming exercise; chronic unpredictable; test ... See more keywords
Dynorphin promotes stress‐induced depressive behaviors by inhibiting ventral pallidal neurons in rats
Sign Up to like & getrecommendations! Published in 2022 at "Acta Physiologica"
DOI: 10.1111/apha.13882
Abstract: Endogenous dynorphin signaling via kappa opioid receptors (KORs) plays a key role in producing the depressive and aversive consequences of stress. We investigated the behavioral effects of the dynorphin/KOR system in the ventral pallidum (VP)… read more here.
Keywords: promotes stress; depressive behaviors; induced depressive; stress induced ... See more keywords
Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice
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DOI: 10.1186/s13041-020-00703-4
Abstract: Sirtuin 1 (SIRT1), is a nicotinamide adenine dinucleotide (NAD + )-dependent protein deacetylase and a candidate gene for depression. Nicotinamide (NAM), a form of vitamin B3, is reported as a potential inhibitor of SIRT1. Our… read more here.
Keywords: independent sirt1; depression; depressive behaviors; sirt1 activity ... See more keywords