Tandem deprotection/coupling for peptide synthesis in water at room temperature
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DOI: 10.1039/c7gc01575e
Abstract: A tandem deprotection/coupling sequence is reported for solution-phase peptide synthesis in water under micellar catalysis conditions using the designer surfactant TPGS-750-M. Cbz deprotection followed by peptide coupling in the presence of COMU and 2,6-lutidine afforded… read more here.
Keywords: tandem deprotection; synthesis water; deprotection; peptide synthesis ... See more keywords