Anti‐hypertensive mechanisms of cyclic depsipeptide inhibitor ligands for Gq/11 class G proteins
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DOI: 10.1016/j.phrs.2019.01.012
Abstract: &NA; Augmented vasoconstriction is a hallmark of hypertension and is mediated partly by hyper‐stimulation of G protein couple receptors (GPCRs) and downstream signaling components. Although GPCR blockade is a key component of current anti‐hypertensive strategies,… read more here.
Keywords: hypertensive mechanisms; cyclic depsipeptide; anti hypertensive; depsipeptide inhibitor ... See more keywords