Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26964
Abstract: Monoclonal antibody interchain disulfide bond reduction was observed in a Chinese Hamster Ovary manufacturing process that used single‐use technologies. A similar reduction has been reported for processes that involved high mechanical shear recovery unit operations,… read more here.
Keywords: reduction; disulfide bond; depth filtration; bond reduction ... See more keywords
Asymmetric depth‐filtration: A versatile and scalable method for high‐yield isolation of extracellular vesicles with low contamination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12256
Abstract: Abstract We developed a novel asymmetric depth filtration (DF) approach to isolate extracellular vesicles (EVs) from biological fluids that outperforms ultracentrifugation and size‐exclusion chromatography in purity and yield of isolated EVs. By these metrics, a… read more here.
Keywords: extracellular vesicles; depth filtration; asymmetric depth; method ... See more keywords
Depth filtration of airborne agglomerates using electrospun bio-based polylactide membranes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2017.12.070
Abstract: Abstract We have investigated the filtration properties of electrospun bio-based polylactide air filter membranes by studying the kinetics of filtration and the influence of fiber diameter, fiber size, and the nature of dust particles on… read more here.
Keywords: filtration; depth filtration; filtration airborne; electrospun bio ... See more keywords