Early Tumor Shrinkage and Depth of Response as Predictive Markers of Treatment Response and Prognosis in Solid Tumors
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DOI: 10.1002/cam4.71251
Abstract: Evaluation of tumor efficacy is central to cancer care. Progression‐free survival (PFS) is widely used as an early surrogate for treatment effectiveness, but more timely and reliable biomarkers are needed. Early tumor shrinkage (ETS) and… read more here.
Keywords: treatment; response; tumor shrinkage; depth response ... See more keywords
Depth of response prior to autologous stem cell transplantation predicts survival in light chain amyloidosis
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DOI: 10.1038/s41409-020-01136-2
Abstract: The goal of therapy in AL amyloidosis is to inhibit further production of the amyloidogenic light chains, thereby allowing organ recovery and improving survival. We aimed to assess the impact of depth of hematologic response… read more here.
Keywords: response; depth response; light; amyloidosis ... See more keywords
Effect of Early Tumor Shrinkage and Depth of Response on the Clinical Outcomes of Patients with Unresectable Hepatocellular Carcinoma Treated with Transcatheter Arterial Chemoembolization and Lenvatinib plus PD-1 Inhibitors
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DOI: 10.1159/000545210
Abstract: Abstract Introduction: Systematic therapies, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), have now been approved as the mainstay treatment for patients with unresectable hepatocellular carcinoma (uHCC). However, only a minority of the… read more here.
Keywords: treatment; clinical outcomes; depth response; hepatocellular carcinoma ... See more keywords
Impact of Pre-Transplant Depth of Response on Outcomes in Patients with Multiple Myeloma: A Report on Behalf of Pakistan Blood and Marrow Transplant Group
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DOI: 10.1182/blood-2024-206627
Abstract: Background: Newly diagnosed transplant eligible multiple myeloma (MM) patients, receive treatment prior to autologous stem cell transplant (ASCT) transplant for a finite period. Retrospective studies have shown improved progression free survival with deeper pre-ASCT responses.… read more here.
Keywords: response; transplant; depth response; transplant depth ... See more keywords
Depth of response and progression free survival in CLL patients on ibrutinib.
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DOI: 10.1200/jco.2018.36.15_suppl.7514
Abstract: 7514Background: While it has been established that attainment of a complete response (CR) after chemoimmunotherapy improves progression free survival (PFS), this has not been proven with the BTK in... read more here.
Keywords: depth response; free survival; progression free; response progression ... See more keywords
Minimal residual disease clinical monitoring and depth of response in multiple myeloma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.8026
Abstract: 8026 Background: MRD assessment is a known surrogate marker for survival in multiple myeloma (MM). Most data come from patients enrolled in clinical trials. We present a single institution’s experience assessing MRD in patients receiving… read more here.
Keywords: response; monitoring; multiple myeloma; disease ... See more keywords
Prognostic impact of depth of response in Waldenström macroglobulinemia patients treated with fixed duration chemoimmunotherapy.
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DOI: 10.1200/jco.2021.39.15_suppl.8049
Abstract: 8049 Background: The treatment paradigm of Waldenström macroglobulinemia (WM) continues to evolve as new therapies expand our options for this indolent and incurable disease. While more profound responses are generally associated with longer treatment-free intervals,… read more here.
Keywords: therapy; response; major response; impact depth ... See more keywords
A narrative review: depth of response as a predictor of the long-term outcomes for solid tumors
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DOI: 10.21037/tcr-20-2547
Abstract: Response Evaluation Criteria in Solid Tumors (RECIST 1.1) is classical and popular for public. However, there are some problems recently. For example, partial response ranges from 30% to 99%, objective response is dichotomous, so there… read more here.
Keywords: cancer; response; predictor long; solid tumors ... See more keywords
Depth of Response was Associated with Progression-Free Survival in Patients with Advanced Non-small Cell Lung Cancer treated with EGFR-TKI
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DOI: 10.7150/jca.33450
Abstract: Background: Response Evaluation Criteria in Solid Tumors (RECIST) has been widely utilized to evaluate new therapeutic strategies in cancer. However, RECIST fails to assess the heterogeneity of response in highly active therapies. Depth of response… read more here.
Keywords: response; depth response; treated egfr; cancer ... See more keywords