Deregulation of SPOP in cancer.
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DOI: 10.1158/0008-5472.can-22-2801
Abstract: Speckle-type POZ protein (SPOP) is a substrate-binding adaptor of the CULLIN3/RING-box1 E3 ubiquitin ligase complex. SPOP is frequently mutated in prostate cancer (PCa) and endometrial cancer (ECa) while it is overexpressed in renal cell carcinoma… read more here.
Keywords: spop; cancer; deregulation spop; spop cancer ... See more keywords