An octimibate derivative, Oxa17, enhances cholesterol efflux and exerts anti-inflammatory and atheroprotective effects in experimental atherosclerosis.
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DOI: 10.1016/j.bcp.2021.114581
Abstract: Atherosclerotic cardiovascular diseases (ASCVDs), associated with vascular inflammation and lipid dysregulation, are responsible for high morbidity and mortality rates globally. For ASCVD treatment, cholesterol efflux plays an atheroprotective role in ameliorating inflammation and lipid dysregulation.… read more here.
Keywords: anti inflammatory; octimibate derivative; derivative oxa17; atherosclerosis ... See more keywords