A 1,2,3-Triazole Derivative of Quinazoline Exhibits Antitumor Activity by Tethering RNF168 to SQSTM1/P62.
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DOI: 10.1021/acs.jmedchem.2c00432
Abstract: Quinazoline and its derivatives have drawn much attention in the development of potential antitumor agents. Here, we synthesized a series of 1,2,3-triazole derivatives of quinazoline at the C6 position and evaluated for their cytotoxic activity… read more here.
Keywords: derivative quinazoline; rnf168; sqstm1 p62; quinazoline ... See more keywords