GREEN SYNTHESIS OF NEW SULFANYL DERIVATIVES OF AMPYRONE AND PREDICTION OF THEIR ANTI-INFLAMMATORY ACTIVITY
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DOI: 10.1007/5472
Abstract: A selective method was developed for the synthesis of acyclic sulfanyl derivatives of ampyrone by thiomethylation reaction of 4-amino- 2,3-dimethyl-1-phenyl-3-pyrazolin-5-one with formaldehyde and thiols in aqueous medium under various conditions (room temperature, 80°C, ultrasonication or… read more here.
Keywords: derivatives ampyrone; anti inflammatory; sulfanyl derivatives; inflammatory activity ... See more keywords