Motuporamine Derivatives as Antimicrobial Agents and Antibiotic Enhancers against Resistant Gram‐Negative Bacteria
Sign Up to like & getrecommendations! Published in 2017 at "Chembiochem"
DOI: 10.1002/cbic.201600532
Abstract: Dihydromotuporamine C and its derivatives were evaluated for their in vitro antimicrobial activities and antibiotic enhancement properties against Gram‐negative bacteria and clinical isolates. The mechanism of action of one of these derivatives, MOTU‐N44, was investigated against… read more here.
Keywords: motuporamine derivatives; agents antibiotic; antimicrobial agents; gram negative ... See more keywords
Phloroglucinol and Its Derivatives: Antimicrobial Properties toward Microbial Pathogens.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00532
Abstract: Phloroglucinol (PG) is a natural product isolated from plants, algae, and microorganisms. Aside from that, the number of PG derivatives has expanded due to the discovery of their potential biological roles. Aside from its diverse… read more here.
Keywords: phloroglucinol derivatives; toward microbial; derivatives antimicrobial; antimicrobial properties ... See more keywords
Synthesis of Some New Substituted Thieno[2,3-d]pyrimidine Derivatives as Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2019 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363219070247
Abstract: A series of thieno-pyrimidine derivatives are synthesized from 5′-amino-2,3′-bithiophene-4′-carboxylate via the corresponding intermediate N-benzoylated carboxamide derivatives. The target compounds are tested for antibacterial and antifungal activity. Some of the synthesized compounds demonstrate potent antibacterial activity… read more here.
Keywords: thieno pyrimidine; derivatives antimicrobial; substituted thieno; synthesis new ... See more keywords
NEW ISONIAZID DERIVATIVES FOR ANTIMICROBIAL SPECTRUM EXTENSION AND HEPATOTOXICITY REDUCTION OF PARENT COMPOUND: IN VITRO AND IN VIVO ASSAYS
Sign Up to like & getrecommendations! Published in 2020 at "Farmacia"
DOI: 10.31925/farmacia.2020.3.20
Abstract: One of the most common adverse effects, in the case of medicines used voluntarily or not, of over dosage, or even of drugs administered in therapeutic doses, is hepatic injury, which is why, in the… read more here.
Keywords: new isoniazid; vivo; isoniazid derivatives; vitro ... See more keywords
Contribution of Aldehydes and Their Derivatives to Antimicrobial and Immunomodulatory Activities
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DOI: 10.3390/molecules27113589
Abstract: Essential oils (EOs) are intricate combinations of evaporative compounds produced by aromatic plants and extracted by distillation or expression. EOs are natural secondary metabolites derived from plants and have been found to be useful in… read more here.
Keywords: immunomodulatory activities; antimicrobial immunomodulatory; contribution aldehydes; aldehydes derivatives ... See more keywords
Enoxacin-based derivatives: antimicrobial and antibiofilm agent: a biology-oriented drug synthesis (BIODS) approach.
Sign Up to like & getrecommendations! Published in 2022 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0065
Abstract: Background: To find alternative molecules against Klebsiella pneumonia, Proteus mirabilis and methicillin-resistant Staphylococcus aureus, new enoxacin derivatives were synthesized and screened. Methods: All derivatives exhibited promising antibacterial activities as compared to standard enoxacin (2 μg/ml) and… read more here.
Keywords: enoxacin based; antimicrobial antibiofilm; based derivatives; derivatives antimicrobial ... See more keywords
Biological Evaluation of 2, 5-Di (4 Aryloylaryloxy Methyl) - 1, 3,4-Oxadiazoles Derivatives as Antimicrobial Agents
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DOI: 10.4172/2161-0444.1000438
Abstract: A series of potential biologically active substituted 2,5-di(4 aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a-j were evaluated for its potential antimicrobial activity comparing with the standard drugs-Streptomycin and Ketoconazole respectively. Compound 9a with fluoro group exhibited highest activity against both… read more here.
Keywords: biological evaluation; oxadiazoles derivatives; evaluation aryloylaryloxy; methyl oxadiazoles ... See more keywords