Polyphthalaldehyde: Synthesis, Derivatives, and Applications.
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DOI: 10.1002/marc.201700519
Abstract: o-Phthalaldehyde is, to this day, the only aromatic aldehyde that can be homopolymerized through chain-growth polymerization. The product, polyphthalaldehyde (PPA), is a brittle white solid, and, having a polyacetal main chain, presents the ability to… read more here.
Keywords: ppa; polyphthalaldehyde synthesis; chemistry; synthesis derivatives ... See more keywords
Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15050511
Abstract: We report efficient synthetic methodologies for the preparation of 3-amino and 3-hydroxy 3-pyrrolin-2-ones (unsaturated γ-lactams) through a multicomponent reaction of amines, aldehydes and acetylene or pyruvate derivatives. The densely substituted γ-lactam substrates show in vitro… read more here.
Keywords: synthesis unsaturated; lactam derivatives; derivatives applications; unsaturated lactam ... See more keywords