Synthesis and Cytotoxic Evaluation of Novel Ester Derivatives of Betulin with AZT, d4T, and 3TC
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DOI: 10.1177/1934578x1701200613
Abstract: Novel ester derivatives of betulin with AZT, d4T, and 3TC were synthesized and assessed for antitumor activities against the KB and HepG2 human cancer cell lines in vitro by MTT assay. Some derivatives displayed high… read more here.
Keywords: betulin azt; novel ester; azt d4t; ester derivatives ... See more keywords
Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde
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DOI: 10.3390/ijms20061372
Abstract: A series of 3-substituted derivatives of betulin and betulinic aldehyde were synthesized as promising anticancer agents. The newly triterpenes were tested against five human cancer cell lines like biphenotypic B myelomonocytic leukaemia (MV-4-11), adenocarcinoma (A549),… read more here.
Keywords: biological activity; betulin betulinic; activity silico; betulinic aldehyde ... See more keywords