2D-QSAR Modeling and Molecular Docking Studies on 1H-Pyrazole-1-carbothioamide Derivatives as EGFR Kinase Inhibitors
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DOI: 10.1021/acsomega.0c01323
Abstract: Epidermal growth factor receptor (EGFR) kinase has been commonly associated with cancers such as lung, ovarian, hormone-refractory prostate, metastatic colorectal, glioblastoma, pancreatic, and breast cancers. A series of 1H-pyrazole-1-carbothioamide derivatives and their EGFR inhibitory activities… read more here.
Keywords: pyrazole carbothioamide; kinase inhibitors; kinase; derivatives egfr ... See more keywords