Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities.
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DOI: 10.1016/j.ejmech.2019.111887
Abstract: The current treatment of Chagas disease is based on the use of two drugs, nifurtimox (Nfx) and benznidazole (Bnz), both of which present limited efficacy in the chronic stage of the disease and toxic side… read more here.
Keywords: nitroimidazole derivatives; genotoxic activities; derivatives evaluated; novel nitroimidazole ... See more keywords