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Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis, in vitro biological evaluation, and in silico ADMET analysis with molecular modeling simulations

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Published in 2023 at "RSC Advances"

DOI: 10.1039/d3ra00297g

Abstract: Recently, scientists developed a powerful strategy called “one drug-multiple targets” to discover vital and unique therapies to fight the most challenging diseases. Novel derivatives of isatin-based Schiff bases 2–7 have been synthesized by the reaction… read more here.

Keywords: schiff bases; derivatives isatin; based schiff; isatin based ... See more keywords