Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry.
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DOI: 10.1021/acs.jmedchem.7b00016
Abstract: The specificity of nucleic acids' binders is crucial for developing this kind of drug, especially for novel G-quadruplexes' binders. Quindoline derivatives have been developed as G-quadruplex stabilizers with good interactive activities. In order to improve… read more here.
Keywords: myc quadruplex; derivatives myc; chemistry; discovery novel ... See more keywords