Exploring Jolkinol D Derivatives To Overcome Multidrug Resistance in Cancer.
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DOI: 10.1021/acs.jnatprod.6b01084
Abstract: Macrocyclic monoacyl lathyrane derivatives bearing a benzoyl moiety were previously found to be strong ABCB1 modulators. To explore the effects of different substituents of the aromatic moiety, 14 new compounds (1.1-1.7, 1.10, and 2.1-2.4) were… read more here.
Keywords: overcome multidrug; exploring jolkinol; jolkinol derivatives; derivatives overcome ... See more keywords