Novel nitric oxide-releasing derivatives of pyranocarbazole as antitumor agents: Design, synthesis, biological evaluation, and nitric oxide release studies.
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DOI: 10.2139/ssrn.4159645
Abstract: In this study, a series of novel furoxan-based nitric oxide (NO) releasing derivatives of pyranocarbazole alkaloids were designed, synthesized, and biologically evaluated against human cancer cell lines. The derivatives showed considerable antiproliferative activities (IC50 = 0.05-7.55 μM) and… read more here.
Keywords: releasing derivatives; nitric oxide; mda 231; derivatives pyranocarbazole ... See more keywords