The monoamine oxidase inhibition properties of C6-mono- and N3/C6-disubstituted derivatives of 4(3H)-quinazolinone.
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DOI: 10.1016/j.bioorg.2018.12.030
Abstract: Parkinson's disease is characterised by the death of the nigrostriatal neurons and depletion of striatal dopamine. The standard symptomatic therapy consists of dopamine replacement with l-dopa, the metabolic precursor of dopamine, which represents the most… read more here.
Keywords: mono disubstituted; disubstituted derivatives; derivatives quinazolinone; monoamine oxidase ... See more keywords