Piperazine‐Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens
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DOI: 10.1002/cmdc.202200385
Abstract: Ketoconazole (KTZ) is an imidazole drug applied topically to treat numerous skin infections. However, as a systemic antifungal, KTZ′ efficacy and safety no longer justify its use as a first‐line treatment. Azole conjugates often display… read more here.
Keywords: piperazine modified; modified ketoconazole; show increased; derivatives show ... See more keywords