Novel [1,2,3]triazolo[1,5-a]pyridine derivatives are trypanocidal by sterol biosynthesis pathway alteration.
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DOI: 10.4155/fmc-2018-0242
Abstract: Aim: To study a new series of [1,2,3]triazolo[1,5-α]pyridine derivatives as trypanocidal agents because current antichagasic pharmacologic therapy is only partially effective. Materials & methods: The effect of the series upon Trypanosoma cruzi epimastigotes and murine… read more here.
Keywords: biosynthesis pathway; triazolo pyridine; sterol biosynthesis; derivatives trypanocidal ... See more keywords