Simultaneous quantification of fatty acids in serum with dual derivatization by Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202300003
Abstract: Fatty acids have multitudinous biological functions and play a crucial role in many biological processes, but due to poor ionization efficiency and lack of appropriate internal standard, the comprehensive quantification of fatty acids by liquid… read more here.
Keywords: chromatography tandem; acids serum; liquid chromatography; quantification fatty ... See more keywords
Letter to the Editor regarding “Comparison of two derivatization-based methods for solid-phase microextraction-gas chromatography-mass spectrometric determination of bisphenol A, bisphenol S, and biphenol migrated from food cans”
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1438-3
Abstract: A few years ago while investigating the GC-MS method for bisphenol S (BPS) in order to expand our existing GCMS method for bisphenol A (BPA) to other bisphenols, it was observed that the work on… read more here.
Keywords: column; bisphenol; two derivatization; based methods ... See more keywords
Benzoyl chloride derivatization improves selectivity and sensitivity of lipidomic quantitation in human serum of pancreatic cancer patients using RP-UHPLC/MS/MS.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical and bioanalytical chemistry"
DOI: 10.1007/s00216-025-06151-0
Abstract: Chemical derivatization is a powerful strategy for enhancing the chromatographic behavior and mass spectrometric sensitivity of lipids, which play an essential role in cellular processes and show high potential in cancer biomarker research. In this… read more here.
Keywords: benzoyl chloride; cancer; chloride derivatization; sensitivity ... See more keywords
Simple chromatographic determination of aflatoxins in Korean fermented soybean products doenjang, ganjang, and gochujang, with comparison of derivatization methods
Sign Up to like & getrecommendations! Published in 2022 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-022-01045-8
Abstract: Korean fermented soybean products doenjang, ganjang, and gochujang are vulnerable to contamination with aflatoxigenic fungi in the open fermentation environment. Therefore, simple and effective methods to determine aflatoxins (AFs) in these complex food matrices are… read more here.
Keywords: soybean products; korean fermented; fermented soybean; products doenjang ... See more keywords
Determination of glyphosate, aminomethylphosphonic acid, and glufosinate in river water and sediments using microwave-assisted rapid derivatization and LC–MS/MS
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-022-19189-9
Abstract: Glyphosate (N-phosphonomethyl glycine) and glufosinate (ammonium dl-homoalanin- 4-methyl phosphinate) are nonselective, broad-spectrum, and highly polar herbicides that are wildly used for weed control in aquatic systems and vegetation control in non-crop areas. Aminomethylphosphonic acid (AMPA)… read more here.
Keywords: water sediments; river; derivatization; water ... See more keywords
Detection of aristolochic acids based on chemical derivatization and GC–MS/MS
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-025-03197-w
Abstract: Aristolochic acids (AAs) are known as nephrotoxins found in Aristolochia and Asarum. This paper aims to establish a novel method for the determination of aristolochic acid I (AA-I) and aristolochic acid II (AA-II) in Chinese… read more here.
Keywords: detection aristolochic; aristolochic acids; based chemical; derivatization ... See more keywords
Chemoselective Probes Serving as Promising Derivatization Tools in Targeted Metabolomics Research
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Analysis and Testing"
DOI: 10.1007/s41664-020-00125-0
Abstract: Recently, chemoselective probes have gained increasing attention for its superior properties in analyte separation, target compound enrichment, metabolite modification, and derivatization. In this regard, the chemoselective probe is showing great potential in targeted metabolomics research.… read more here.
Keywords: metabolomics research; targeted metabolomics; probes serving; chemoselective probes ... See more keywords
Isotope-dilution liquid chromatography-tandem mass spectrometry for sensitive quantification of human insulin in serum using derivatization-technique.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2017.08.019
Abstract: An isotope-dilution mass spectrometry (IDMS) method for measuring insulin levels in human serum was developed using C-terminal-derivatization method coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS). The carboxyl groups of Glu-C-cleavage products were derivatized with 1-(2-pyrimidinyl)piperazine… read more here.
Keywords: insulin; derivatization; mass spectrometry; serum ... See more keywords
Simultaneous monitoring of the bioconversion from lysine to glutaric acidby ethyl chloroformate derivatization and gas chromatography-mass spectrometry.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113688
Abstract: Glutaric acid is a precursor of a plasticizer that can be used for the production of polyester amides, ester plasticizer, corrosion inhibitor, and others. Glutaric acid can be produced either via bioconversion or chemical synthesis,… read more here.
Keywords: chromatography; bioconversion; glutaric acid; mass ... See more keywords
Derivatization enhanced separation and sensitivity of long chain-free fatty acids: Application to asthma using targeted and non-targeted liquid chromatography-mass spectrometry approach.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.08.009
Abstract: Long chain-free fatty acids (LCFFAs) play pivotal roles in various physiological functions, like inflammation, insulin resistance, hypertension, immune cell behavior and other biological activities. However, the detection is obstructed by the low contents, structural diversity,… read more here.
Keywords: chain free; fatty acids; long chain; non targeted ... See more keywords
Fluorous-paired derivatization approach towards highly sensitive and accurate determination of long chain unsaturated fatty acids by liquid chromatography-tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.09.052
Abstract: Long chain unsaturated fatty acids (LCUFAs) are emerging as critical contributors to inflammation and its resolution. Sensitive and accurate measurement of LCUFAs in biological samples is thus of great value in disease diagnosis and prognosis.… read more here.
Keywords: chain unsaturated; long chain; determination; derivatization ... See more keywords