Gut-derived acetate promotes B10 cells with antiinflammatory effects
Sign Up to like & getrecommendations! Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.144156
Abstract: Autoimmune diseases are characterized by a breakdown of immune tolerance partly due to environmental factors. The short-chain fatty acid acetate, derived mostly from gut microbial fermentation of dietary fiber, promotes antiinflammatory Tregs and protects mice… read more here.
Keywords: promotes b10; cells antiinflammatory; gut derived; derived acetate ... See more keywords
Microbiota-derived acetate attenuates neuroinflammation in rostral ventrolateral medulla of spontaneously hypertensive rats
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-024-03061-3
Abstract: Background Increased neuroinflammation in brain regions regulating sympathetic nerves is associated with hypertension. Emerging evidence from both human and animal studies suggests a link between hypertension and gut microbiota, as well as microbiota-derived metabolites short-chain… read more here.
Keywords: derived acetate; ventrolateral medulla; spontaneously hypertensive; rostral ventrolateral ... See more keywords