The therapeutic potential of targeting CD73 and CD73-derived adenosine in melanoma.
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DOI: 10.1016/j.biochi.2020.06.001
Abstract: The hypoxic environment of melanoma results in CD73 upregulation on the surface of various tumor microenvironment (TME) cells including tumor cells, stromal cells and infiltrated immune cells. Consequently, CD73 through both enzymatic and none enzymatic… read more here.
Keywords: melanoma; cd73 derived; cd73; derived adenosine ... See more keywords