Bifunctional Lipid-Derived Affinity-Based Probes (AfBPs) for Analysis of Lipid-Protein Interactome.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00593
Abstract: ConspectusAlthough lipids are not genetically encoded, they are fundamental building blocks of cell membranes and essential components of cell metabolites. Lipids regulate various biological processes, including energy storage, membrane trafficking, signal transduction, and protein secretion;… read more here.
Keywords: derived affinity; lipid protein; lipid derived; protein interactome ... See more keywords
QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cheminformatics"
DOI: 10.1186/s13321-020-00444-5
Abstract: Affinity fingerprints report the activity of small molecules across a set of assays, and thus permit to gather information about the bioactivities of structurally dissimilar compounds, where models based on chemical structure alone are often… read more here.
Keywords: derived affinity; affinity; qaffp; qsar derived ... See more keywords