MI-derived alarmins activate B cells to accelerate atherosclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-021-00515-6
Abstract: Alarmins released by infarcted myocardium stimulate B cells to differentiate into antibody-producing plasma cells, which then remotely drive the progression of atherosclerosis by producing autoantibodies that accumulate in pre-existing atherosclerotic plaques, increasing local inflammation and… read more here.
Keywords: accelerate atherosclerosis; alarmins activate; cells accelerate; activate cells ... See more keywords
Pathogenic roles of neutrophil‐derived alarmins (S100A8/A9) in heart failure: From molecular mechanisms to therapeutic insights
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15998
Abstract: An excessive neutrophil count is recognized as a valuable predictor of inflammation and is associated with a higher risk of adverse cardiac events in patients with heart failure. Our understanding of the effectors used by… read more here.
Keywords: heart failure; neutrophil derived; derived alarmins; alarmins s100a8 ... See more keywords