Therapeutic activity of plant-derived alkaloid conophylline on metabolic syndrome and neurodegenerative disease models
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DOI: 10.1007/s13577-017-0196-4
Abstract: Increasing metabolic syndromes including type-2 diabetes mellitus, obesity, and steatohepatitis are serious problems in most countries in the world. Neurodegenerative diseases such as Alzheimer, Parkinson’s, and Huntington’s diseases are increasing in many countries. However, therapy… read more here.
Keywords: derived alkaloid; plant derived; alkaloid conophylline; activity plant ... See more keywords
Anti-Mycobacterial N-(2-Arylethyl)quinolin-3-amines Inspired by Marine Sponge-Derived Alkaloid
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DOI: 10.3390/molecules27248701
Abstract: The synthesis and evaluation of simplified analogs of marine sponge-derived alkaloid 3-(phenethylamino)demethyl(oxy)aaptamine were performed to develop novel anti-mycobacterial substances. Ring truncation of the tricyclic benzo[de][1,6]-naphthyridine skeleton effectively weakened the cytotoxicity of the natural product, and… read more here.
Keywords: sponge derived; anti mycobacterial; arylethyl quinolin; marine sponge ... See more keywords